sim_tools.make_bold¶

sim_tools.make_bold(fname, stim_onset=None)[source]¶

Convert raw model output to BOLD signal

Parameters:

Parameters:	fname : str File-name (including path if not in working directory) of HDF5 container that was generated by run_model. stim_onset : float Time (in seconds) of stimulus onset. By default, onset/offset timings of stimuli are stored in the HDF5 container generated by run_model. Only override this setting, if you know what you are doing.
Returns:	Nothing : None The computed BOLD signal is stored as dataset BOLD at the top level of the HDF5 container specified by fname.

fname : str

File-name (including path if not in working directory) of HDF5 container that was generated by run_model.

stim_onset : float

Time (in seconds) of stimulus onset. By default, onset/offset timings of stimuli are stored in the HDF5 container generated by run_model. Only override this setting, if you know what you are doing.

Returns:

Nothing : None

The computed BOLD signal is stored as dataset BOLD at the top level of the HDF5 container specified by fname.

Notes

Regional neural voltages are converted to BOLD time-series using the linear hemodynamic response function proposed by Glover [R10]. For details consult the supporting information of our paper [R11].

References

[R10]

(1, 2) Glover G. Deconvolution of Impulse Response in Event-Related BOLD FMRI. NeuroImage 9: 416-429, 1999.

[R11]

(1, 2) S. Fuertinger, J. C. Zinn, and K. Simonyan. A Neural Population Model Incorporating Dopaminergic Neurotransmission during Complex Voluntary Behaviors. PLoS Computational Biology, 10(11), 2014.